To fill lines and wrinkles, try RESTYLANE® and Restylane® REFYNE™
RESTYLANE® and Restylane® REFYNE™ are dermal fillers that provide long-lasting reduction of lines and wrinkles, such as nasolabial folds (smile lines) and marionette lines (laugh lines).1-4 With RESTYLANE® and Restylane® REFYNE™ you get tailored and natural looking results that leave you filled with confidence.3-4
Why fill with RESTYLANE®?
As we age, our skin becomes thinner and less elastic, and its ability to retain water is reduced. The result is the appearance of fine lines and wrinkles, and you may feel that you look tired, old or sad. Treatments with dermal fillers help to restore and maintain your youthful appearance and regain lost confidence.4-5
RESTYLANE® is a firmer dermal filler that can be used to fill wrinkles where you have good tissue coverage. Restylane® REFYNE™ is a softer and more flexible dermal filler that can be used for treatment of more dynamic areas of your face, for example, around the lips, the nasolabial folds and the marionette lines.4 RESTYLANE® and Restylane® REFYNE™ help you refine your looks and realise your individual needs and desires.
RESTYLANE® and Restylane® REFYNE™ can last up to at least 18 months with one retreatment2,4. The duration of effect will depend on the dose used, area treated, number of touch up treatments and individual patient characteristics.
RESTYLANE® and Restylane® REFYNE™ treatment areas
RESTYLANE® and Restylane® REFYNE™ are dermal fillers that are used to reduce lines and wrinkles and give you a refined and natural look. Areas that can be treated are, for example, fine lines around the mouth and eyes, marionette lines and nasolabial folds.
Your Restylane® treatment
A treatment with Restylane® takes approximately 15-45 minutes, depending on the area that will be treated. Sometimes you might need a touch-up treatment about two weeks after the initial treatment to optimise your results. Most Restylane fillers contain a local anesthetic, lidocaine, that takes away most of the discomfort during treatment.
Immediately after your dermal filler treatment, you may experience some post-treatment side effects, such as redness, swelling, pain, bruising or tenderness at the treatment site. These side effects usually disappear within one week after injection. Though fillers are minimally invasive, they still carry some risks. Before the treatment, you should discuss all possible risks and benefits with your healthcare practitioner.
Restylane® gives you long-lasting but non-permanent results, meaning that you can continuously refine your looks.
How it works
Hyaluronic acid is a substance that has a unique ability to bind water. Hyaluronic acid occurs naturally in our bodies and in all layers of our skin. It keeps your body tissues soft, hydrated and flexible. However, as we age, the body’s ability to produce hyaluronic acid lessens, leading to dry and thinner skin.
Native hyaluronic acid in the body degrades quickly, in one to two days. To make the hyaluronic acid in RESTYLANE® and Restylane® REFYNE™ last longer—for up to 18 months or more with one retreatment3,7—Galderma has used stabilisation technologies that delay degradation.
RESTYLANE® contains a hyaluronic acid gel with a firmer consistency and Restylane® REFYNE™ contains a gel with a more flexible consistency to target different kinds of lines and wrinkles.
RESTYLANE® was the first ever non-animal stabilised hyaluronic acid filler. RESTYLANE® was launched in 1996, a brand that has the longest history on the market compared to other hyaluronic acid dermal filler brands.
Frequently asked questions
How long does the treatment take?
A treatment with Restylane does not take long. Depending on the area and indication, it takes approximately 15-45 minutes. A touch-up treatment is sometimes performed approximately two weeks after the initial treatment to optimize the results.
Is the treatment painful?
Some people may experience mild discomfort. Most Restylane fillers contain an integrated local anesthetic, lidocaine, to provide you with a more comfortable treatment experience. You and your healthcare practitioner may decide whether additional pain relief is needed.
Can everyone have a treatment with Restylane fillers?
Ask your healthcare practitioner if you will benefit from treatment with any of the hyaluronic acid products within the Restylane range. It is important when discussing your medical history to tell your practitioner everything, including all medicines that you are taking, any present and past allergies and their seriousness, and all current or past medical conditions you have had. Your practitioner will discuss potential side effects from the injection of Restylane and how serious they may be. You should also inform your practitioner if you have received previous aesthetic treatments, both surgical and non-surgical.
Who should not have a Restylane filler treatment?
Patients with a known allergy to hyaluronic acid based products should not undergo treatment, nor should patients with bleeding disorders, or active skin disease such as inflammation, infection or tumors in or near the area to be treated. Discuss contraindications, warnings and precautions with your healthcare practitioner before Restylane filler treatments.
Can I have a Restylane filler treatment if I am pregnant?
The Restylane products have not been tested in pregnant or breastfeeding women and is therefore not recommended if you are pregnant or breastfeeding.
What happens after the treatment?
After the treatment you will receive post-treatment guidelines. It is normal to experience some post-treatment discomfort, such as redness, swelling, pain, itching, bruising or tenderness at the treatment site. These side effects generally disappear within one week after injection.
Other potential side effects can occur with dermal fillers based on hyaluronic acid. You should discuss the potential treatment risks with your healthcare practitioner. Following treatment, there is sometimes a need for a touch-up treatment to achieve an optimal result.
Skin insights
Our portfolio of products
Galderma has developed a diverse portfolio of products that work holistically together.
RELAX
Relax the tension of facial muscles associated with frown lines and crow´s feet to show how you truly feel inside.
REFRESH
Refresh your skin from within with a boost of deep hydration, for a refreshed and vibrant look that lasts.
RENEW
Renew the structure of your skin with a collagen activator that gradually builds the foundation of the youthful, firmer you.
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References
- Narins RS et al. Dermatol Surg 2011;37:644–650.
- Rzany B et al. Dermatol Surg 2017;43:58–65.
- Rzany B et al. Dermatol Surg 2012;38:1153–1161.
- Huang S and Tsai T. J Drugs Dermatol. 2020;19(9):836–842.
- Talarico S et al. Dermatol Surg 2015;41:1361–1369.
- Swift A et al. Clin Cosmet Investig Dermatol 2017;10:229–238.
- Philipp-Dormston WG et al. Dermatol Surg 2018;44(6):826-832