For a youthful, firmer you, ask for Sculptra®
Sculptra® stimulates your skin’s own natural collagen and elastin production.1–4 With Sculptra®, you will renew skin thickness and firmness and correct shallow to deep wrinkles and folds.5-9
Sculptra® gradually builds your skin’s structural foundations for radiant, natural-looking, rejuvenated skin.5,8-10

Sculptra® as a collagen biostimulator
Sculptra® is a regenerative biostimulator that stimulates your skin’s ability to produce collagen and elastin, rebuilding your skin’s structure and increasing its natural firmness.1–4, 8-10
Collagen is a fibrous protein in the deeper layers of your skin and is key for youthful-looking skin.11 As you age, your body’s collagen production decreases. The loss of collagen will in time lead to loose and saggy skin, such as jowls, and the formation of facial wrinkles and folds.11
Find out more about collagen, including what it is and what it does for your face and skin.
Sculptra® is the first proven regenerative biostimulator injectable that will renew your skin in a progressive way with natural-looking, long-lasting results, showing improvements for up to 2 years.7, 9,12-14
Treatment areas: Sculptra® for jowls, cheeks, and chin
Sculptra® can help to add volume and firmness to areas of your face that have become loose and saggy.8-11 These treatment areas include jowls, cheeks, smile lines (nasolabial folds), laugh lines (marionette lines), and chin wrinkles.15 Sculptra® regenerative biostimulator treatments help to stimulate collagen and elastin in your skin.3,4
Sculptra® for cheeks
As you age, your skin loses volume, which can result in sunken cheeks. This can be due to a loss of facial fullness, and bone resorption that comes with age.16-18 Because of this, people often seek out collagen treatments to help add volume to their cheeks. Regenerative biostimulator injections, like Sculptra®, help to stimulate your own collagen and elastin production contributing to a more youthful look.3-5,9
Sculptra® for jowls and chin
Your skin also loses some of its elasticity as you age, which alongside bone resorption, moving fat pads, and loss of volume higher up in the face, can result in a sagging jawline.15–17 Sculptra® can help stimulate your body’s own collagen and elastin production in your face, helping to gradually rebuild your skin’s structural foundation.3-5, 10
Sculptra® for wrinkles, deep folds, and lines
Wrinkles on the face also come with aging, as changes to collagen, fat, and bone take place.16-18 Wrinkles and folds, such as deep folds between the nose and mouth (nasolabial folds), and lines framing the mouth (marionette lines) can become more pronounced.11 Sculptra® helps to improve skin thickness and increase skin firmness and has been found to help improve the appearance of wrinkles and folds.1–5,8-10



Your Sculptra® treatment
Sculptra® is injected into the deep layers of your skin to stimulate your skin’s own collagen and elastin production.1–4 You will gradually notice visible improvements in skin firmness and fullness.5,8,9
Immediately after each treatment session, you may experience some swelling that will temporarily reduce wrinkles and folds. Thereafter, the gradual process of collagen replacement starts. Sculptra® works subtly, improving facial areas gradually to give you a youthful and natural-looking result that lasts.
How long does a Sculptra® regenerative biostimulator last?
Sculptra® will reinvigorate your skin and bring back your youthful appearance. Results may last for more than two years.7,9,13
In a clinical study, 80% of users were still satisfied with their Sculptra® collagen regenerative biostimulator treatment 25 months after their last injection.19

How does Sculptra® work to stimulate collagen?
The active ingredient of Sculptra® is a poly-L-Lactic acid, PLLA-SCATM. PLLA-SCATM is a biodegradable substance that has been used for decades in dissolvable stitches for wound management.15,20 When PLLA-SCATM is injected into the deeper layers of your skin, it helps stimulate your skin’s own natural collagen and elastin production.1–4
This results in your skin’s inner structure being improved, and you will regain skin volume that has been lost due to aging.
Sculptra® before and after
View pictures of before and after a Sculptra® treatment. See the differences in hollow cheeks, chin wrinkles, smile and laugh lines, and jowls before and after Sculptra®.

80%
rated Sculptra® as good to excellent after 25 months19
100%
of patients would recommend Sculptra® to a friend5
First approved in Europe in
1999 21,22
Frequently asked questions about Sculptra®
What should I expect from my chosen healthcare practitioner?
Your healthcare practitioner should provide you with comprehensive information about how Sculptra® stimulates the formation of collagen and elastin naturally and give you a detailed explanation regarding your treatment.
This should include:
- Information about the possibilities and limitations of Sculptra® treatment
- Information about possible side effects and precautions for Sculptra®
- Information about the cost of Sculptra® treatments and follow-up treatments
- Answering any question you may have to your satisfaction
How does Sculptra® help with jowls and hollow cheeks?
Sculptra® targets the signs of aging, including sagging jowls and hollow-looking cheeks. The key ingredient, PLLA-SCATM, is injected into the deeper layers of the skin where it gradually stimulates collagen and elastin production.1,3,4 Sculptra® stimulates collagen and elastin production, strengthening the skin’s structure, and improving quality and radiance.4,5,9,10,12 This provides a more youthful contour to the lower face.11
How does Sculptra® improve skin texture?
In addition to structural support, Sculptra® can improve overall skin texture5,10,23 As PLLA-SCATM stimulates collagen and elastin production, it helps improve skin elasticity and firmness.4,5,8,9 This leads to smoother, more even skin texture over time. The gradual build-up of collagen can also reduce the visibility of fine lines and wrinkles, contributing to a revitalized and rejuvenated appearance.10,23
Which areas does Sculptra® treat?
Sculptra® is injected to correct shallow to deep wrinkles, folds, and jowls by stimulating the skin’s own collagen and elastin production.1-4 Administered with the appropriate injection technique from a trained specialist, Sculptra is clinically approved for:
- Deep folds between the nose and mouth (nasolabial folds), also called “smile lines”
- Lines framing the mouth (marionette lines)
- Sagging cheeks and jowls
- Chin and cheek wrinkles
Please note that indications vary between countries. Please consult your healthcare practitioner for more information.
Can Sculptra® stimulate collagen production under the eyes?
Sculptra® is proven to work in the lower face area including the cheeks and chin.15 If you’re looking for something to help with your under-eye area, Restylane® EYELIGHT is a targeted filler for the tear trough area under your eyes.24
Can Sculptra® collagen biostimulators be used around the nose and mouth?
Sculptra® is injected to correct shallow to deep wrinkles, folds, and jowls and can be used for the deep folds between the nose and mouth (nasolabial folds), also called smile lines as well as the lines framing the mouth, called marionette lines.
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References
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- Goldberg D et al. Dermatol Surg. 2013;39(6):915-922.
- Huth S et al. J Drugs Dermatol. 2024;23(4):285-288.
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- Galderma Data on File MA-48830.
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- US Patent 7731758 B2 (v1.0).
- Sculptra IFU.
- Haddad Aet al. J Drugs Dermatol. 2019;18(9):929-935.
- Reece EM and Rohrich RJ. Aesthet Surg J. 2008;28(6):668-674.
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- Brown SA et al. Plast Reconstr Surg. 2011;127(4):1684-1692.
- Chen HL et al. Adv Skin Wound Care. 2023;36(9):1-8.
- Galderma Data on File MA-54151 ISO - 13485 (v1.0).
- FDA Marketing approval Sculptra (v1.0).
- Guarnieri Munia C et al. J Clin Aesthet Dermatol. 2023;16(6):26-29.
- Restylane Eyelight IFU.
- Humphrey CD, Lawrence AC. Facial Plast Surg. 2023 Dec;39(6):719–21.
- Palm M et al. J Drugs Dermatol. 2021;20(7):760-766.
- Galderma Data on File MA-46589 (v1.0).
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