For a youthful, firmer you, ask for Sculptra®
Sculptra® stimulates your skin’s own natural collagen and elastin production.1–4 With Sculptra®, you will renew skin thickness and firmness and correct shallow to deep wrinkles and folds.5-9
Sculptra® gradually builds your skin’s structural foundations for radiant, natural-looking, rejuvenated skin.5,8-10

Sculptra® as a collagen biostimulator
Sculptra® is a regenerative biostimulator that stimulates your skin’s ability to produce collagen and elastin, rebuilding your skin’s structure and increasing its natural firmness.1–4, 8-10
Collagen is a fibrous protein in the deeper layers of your skin and is key for youthful-looking skin.11 As you age, your body’s collagen production decreases. The loss of collagen will in time lead to loose and saggy skin, such as jowls, and the formation of facial wrinkles and folds.11
Find out more about collagen, including what it is and what it does for your face and skin.
Sculptra® is the first proven regenerative biostimulator injectable that will renew your skin in a progressive way with natural-looking, long-lasting results, showing improvements for up to 2 years.7, 9,12-14
Treatment areas: Sculptra® for jowls, cheeks, and chin
Sculptra® can help to add volume and firmness to areas of your face that have become loose and saggy.8-11 These treatment areas include jowls, cheeks, smile lines (nasolabial folds), laugh lines (marionette lines), and chin wrinkles.15 Sculptra® regenerative biostimulator treatments help to stimulate collagen and elastin in your skin.3,4
Sculptra® for cheeks
As you age, your skin loses volume, which can result in sunken cheeks. This can be due to a loss of facial fullness, and bone resorption that comes with age.16-18 Because of this, people often seek out collagen treatments to help add volume to their cheeks. Regenerative biostimulator injections, like Sculptra®, help to stimulate your own collagen and elastin production contributing to a more youthful look.3-5,9
Sculptra® for jowls and chin
Your skin also loses some of its elasticity as you age, which alongside bone resorption, moving fat pads, and loss of volume higher up in the face, can result in a sagging jawline.15–17 Sculptra® can help stimulate your body’s own collagen and elastin production in your face, helping to gradually rebuild your skin’s structural foundation.3-5, 10
Sculptra® for wrinkles, deep folds, and lines
Wrinkles on the face also come with aging, as changes to collagen, fat, and bone take place.16-18 Wrinkles and folds, such as deep folds between the nose and mouth (nasolabial folds), and lines framing the mouth (marionette lines) can become more pronounced.11 Sculptra® helps to improve skin thickness and increase skin firmness and has been found to help improve the appearance of wrinkles and folds.1–5,8-10



Your Sculptra® treatment
Sculptra® is injected into the deep layers of your skin to stimulate your skin’s own collagen and elastin production.1–4 You will gradually notice visible improvements in skin firmness and fullness.5,8,9
Immediately after each treatment session, you may experience some swelling that will temporarily reduce wrinkles and folds. Thereafter, the gradual process of collagen replacement starts. Sculptra® works subtly, improving facial areas gradually to give you a youthful and natural-looking result that lasts.
How long does a Sculptra® regenerative biostimulator last?
Sculptra® will reinvigorate your skin and bring back your youthful appearance. Results may last for more than two years.7,9,13
In a clinical study, 80% of users were still satisfied with their Sculptra® collagen regenerative biostimulator treatment 25 months after their last injection.19

How does Sculptra® work to stimulate collagen?
The active ingredient of Sculptra® is a poly-L-Lactic acid, PLLA-SCATM. PLLA-SCATM is a biodegradable substance that has been used for decades in dissolvable stitches for wound management.15,20 When PLLA-SCATM is injected into the deeper layers of your skin, it helps stimulate your skin’s own natural collagen and elastin production.1–4
This results in your skin’s inner structure being improved, and you will regain skin volume that has been lost due to aging.
Sculptra® before and after
View pictures of before and after a Sculptra® treatment. See the differences in hollow cheeks, chin wrinkles, smile and laugh lines, and jowls before and after Sculptra®.

80%
rated Sculptra® as good to excellent after 25 months19
100%
of patients would recommend Sculptra® to a friend5
First approved in Europe in
1999 21,22
Frequently asked questions about Sculptra®
Does Sculptra® add volume to the face?
Sculptra® helps to restore lost facial volume and improve skin firmness, which can diminish the appearance of wrinkles, jowls, and hollow-looking areas such as in your cheeks.
Can I use Sculptra® after weight loss?
Yes, Sculptra® can be used to help with any changes to your face that may have taken place during, or after, your weight loss journey. Weight loss can leave you with a hollow and gaunt face and Sculptra® can help restore structure to your face. 5,9,10,25
After a rapid drop down in weight, a glow-up with biostimulators can help you restore facial volume and improve skin quality.
Galderma has more than two decades of scientific expertise in addressing the impacts of rapid weight loss,15,26,27 starting with our clinically proven regenerative biostimulator, Sculptra® (PLLA-SCA™), a treatment originally used to restore or correct the signs of facial lipoatrophy.10,15
Always consult your healthcare professional for individualized treatment recommendations and to discuss important safety information and risks associated with the use of the products.
Does Sculptra® lift the face?
Because Sculptra® is a collagen and elastin regenerative biostimulator, it helps to firm the skin and add volume to your face, which can help provide the appearance of lift to your face.5,9
How many Sculptra® collagen biostimulator treatments are required?
Repeated Sculptra® treatments rejuvenate and improve skin quality.9 The number of injections at each session will vary, depending on the degree of correction needed, and the treatment plan determined by you and your healthcare practitioner.
Will the Sculptra® treatment be painful?
As with any injection, some pain at the treatment site is possible, but your healthcare practitioner may use a topical anesthetic to ease any discomfort.
How soon will I see results?
Sculptra® is designed to give you noticeable results that emerge gradually with increased collagen production. Don’t be disappointed if you don’t see immediate results. A few days after treatment, you may look as you did before treatment. This is normal and temporary. Because results happen gradually, you will see subtle, yet noticeable results in the reduction of facial wrinkles and folds.* Patients reported skin improvement 1 month after treatment showing improvement after 3 months, 1 year, and 2 years.9
*Safety and effectiveness of Sculptra® have not been evaluated in areas other than nasolabial wrinkles and folds.
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References
- Stein P et al. J Dermatol Sci. 2015;78(1):26-33.
- Goldberg D et al. Dermatol Surg. 2013;39(6):915-922.
- Huth S et al. J Drugs Dermatol. 2024;23(4):285-288.
- Widgerow A et al_IMCAS 2024.
- Mest DR and Humble G. Dermatol Surg. 2006;32(11):1336-1345.
- Valantin MA et al. AIDS. 2003;17(17):2471-2477.
- Narins RS et al. J Am Acad Dermatol. 2010;62(3):448-462.
- Hexsel D et al. Dermatol Surg. 2020;46(8):1122-1124.
- Fabi S et al. J Drugs Dermatol. 2024;23(1):1297-1305.
- Bohnert K et al. Dermatol Surg. 2019;45(5):718-724.
- Fisher GJ et al. Arch Dermatol. 2008;144(5):666-672.
- Galderma Data on File MA-48830.
- Brandt FS et al. Aesthet Surg J. 2011;31(5):521-528.
- US Patent 7731758 B2 (v1.0).
- Sculptra IFU.
- Haddad Aet al. J Drugs Dermatol. 2019;18(9):929-935.
- Reece EM and Rohrich RJ. Aesthet Surg J. 2008;28(6):668-674.
- Zhang S and Duan E. Cell Transplant. 2018;27(5):729-738.
- Brown SA et al. Plast Reconstr Surg. 2011;127(4):1684-1692.
- Chen HL et al. Adv Skin Wound Care. 2023;36(9):1-8.
- Galderma Data on File MA-54151 ISO - 13485 (v1.0).
- FDA Marketing approval Sculptra (v1.0).
- Guarnieri Munia C et al. J Clin Aesthet Dermatol. 2023;16(6):26-29.
- Restylane Eyelight IFU.
- Humphrey CD, Lawrence AC. Facial Plast Surg. 2023 Dec;39(6):719–21.
- Palm M et al. J Drugs Dermatol. 2021;20(7):760-766.
- Galderma Data on File MA-46589 (v1.0).
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