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THE REGENERATIVE BIOSTIMULATOR THAT RENEWS SKIN FROM WITHIN1-6
Aesthetic goals are evolving, 7-10 with people moving beyond facial rejuvenation and age-related concerns toward solutions that elevate body confidence at every stage of life. 11-14 Sculptra® goes beyond simply addressing wrinkles — it strengthens the skin’s foundation for a healthier looking appearance. 15-21
Treatment can be tailored to your goals, whether you wish to improve skin quality, firmness, volume, contour, or a subtle lifting effect. 15,22-31 As the first proven regenerative biostimulator, Sculptra® re-engages your skin’s natural renewal process, stimulating collagen and elastin to progressively enhance firmness, shape, and contour for a naturally sculpted look. 1,6,15-16,19,24-31,33-34,36,38-41
Sculptra® is a unique regenerative biostimulator that is made with the plant-based PLLA-SCA™ formulation.1,38-39,41-42 which works across all 3 skin layers of the skin to renew healthy tissue.36,43-45
Sculptra® targets key components of the skin required to combat signs of aging, including stimulating your own collagen and elastin, with a positive impact on healthy fat.36,40,43-44,46-48
From face to body, Sculptra® helps improve skin firmness, smoothness and radiance — enhancing natural-looking shape and supporting long-lasting confidence. 1,15-16,21,34-35,49-53
Restore natural-looking firmness, smoothness and volume while improving radiance and skin quality — for results that last for more than 2 years. 1,6, 15,19,33-34,54
Firm, smooth and contour areas such as the arms, posterior thighs, buttocks and décolletage. Patients reported seeing improvements as early as one month after treatment, with continued improvement observed at 2 months and 1 year.*
*Cellulite in the posterior thighs 1,27,30-31, 55-62
Look and feel better with skin that feels like you again—for a long time. People are still satisfied with their facial results more than 2 years after treatment.15, 33-34
For the body, improvements in firmness, smoothness and cellulite appearance are still visible one year after treatment.30
Increase in type I collagen at 3 months - the most important collagen in relation to skin aging40
Patients who were still satisfied 2 years after treatment15
Patients who saw firmer skin on the body one year after treatment30
Discover real stories from real patients who embarked on a personal journey with Sculptra® over one year.
Follow patients' Sculptra® Stories and hear what they and their healthcare practitioners have to say about Sculptra®.
Achieve the look you envision by speaking to
a healthcare practitioner today.
1. Sculptra MDR EU IFU 2. Galderma Receives FDA Approval for New SCULPTRA® Label. Galderma 2021. 3. Asius J et al. US patent US 7,731,758 B22(010):2010. 4.Sanofi S.r.l. DEKRA EN ISO 13485:2016 Certificate. Effective Feb 2023. 5.Zhang Y et al. Regen Biomater. 2021;8(5):rbab042. 6.Widgerow A et al. Comparative gene-signature study of PLLA-SCA vs CaHA. Poster, IMCAS 2024 7.Cohen JL, et al. J Cosmet Dermatol. 2023;22(11):2889-2901. 8. Facial Plastic Surgery (2023) As Americans return to the office, AAFPRS unveils aesthetics trends from annual facial plastic surgery survey [Online]. Available at: https://www.aafprs.org/Media/Press_Releases/New-Trends-in-Facial-Plastic-Sur- gery.aspx [Accessed: October 2025]. WGSN (2019) Gen Z: Building New Beauty [Online]. Available at: https://www.wgsn.com/assets/marketing/emails/2019/beauty/ launch/Beauty_Whitepaper_Digital.pdf [Accessed: October 2025]. 10.Liew S, et al. Aesth Plast Surg 2016;40(2):193–201. 1.Triana L, et al. Aesthetic Plast Surg. 2024;48(20):4217-4227. 12. El Hawa M, et al. J Cosmet Dermatol. 2025;24(1):e16624. 13.Fares C, et al. J Cosmet Dermatol. 2025;24(2):e16671. 14.Fabi S. Fillers for the Décolletage Area. https://assets.bmctoday.net/practicaldermatology/pdfs/PD0915_CF_Fillers.pdf [Accessed: October 2025] 15.Fabi S, et al. Poster presented at IMCAS World Congress. 26 -28 January 2023. Paris, France. 16.Bohnert K, et al. Plast Reconstr Surg. 2019;45(5):718–24. 17.Vleggaar D, et al. J Drugs Dermatol. 2008;7(3):209 -20. 18. Li Y, et al. Front Physiol. 2024;15:1346612. 19.Mest DR, Humble G. Dermatol. Surg. 2006;32(11):1336–45.20. Galderma. Data on file (MA-48830). 21. Hexsel D, et al. Dermatol Surg. 2020;46(8):1122–4. 22. Haddad, A et al. Poster presented at IMCAS World Congress. 01-03 February 2024. Paris, France. 23. Bohnert K, et al. Plast Reconstr Surg. 2019;127(4):1684–1692. 24. Fabi S, et al. Dermatol Surg. 2024;50(12):1137-1142. 25. Valantin MA, et al. AIDS. 2003;17(17):2471–7. 26. Sarubi J,et al. J Clin Aesthet Dermatol. 2023;16(6):30-36. 27. Mazzuco R, Sadick NS. Dermatol Surg. 2016;42(3):441-443.28.Munia C, et al. J Clin Aesthet Dermatol. 2022;15(7):38-42. 29. Nikolis A, et al. Dermatol Surg. 2025;51(7):702-709. 30. Beleznay K, et al. Poster presented at IMCAS World Congress. 01-03 February 2024. Paris, France. 31. Haddad A, et al. Aesthetic Plast Surg. 2025;49(5):1507-1517. 32.Nikolis A, et al. J Drugs Dermatol. 2022;21(3):295-304. 33.Brandt FS, et al. Aesthet Surg J. 2011;31(5):521–528. 34. Narins RS, et al. J Am Acad Dermatol. 2010;62(3):448–462. 35. Widgerow A, et al. A randomized, comparative study describing the gene signatures of PLLA-SCA™ and CaHA in the treatment of nasolabial folds. Poster presented at IMCAS World Congress; 01–03 Feb 2024; Paris, France.36. Huth S, et al. J Drugs Dermatol. 2024;23(4):285–288.37. FDA. Summary of safety and effectiveness data. Available at: https://www.fda.gov/medicaldevices/recently-approved-devices/sculptra-p030050s039 [Accessed: August 2025]. 38. Data on file (MA-54151).39. Data on file (MA-46589).40. Goldberg D, et al. Dermatol Surg. 2013;39(6):915–922. 41. FDA. Summary of safety and effectiveness data. Available https://www.accessdata.fda.gov/cdrh_docs/pdf3/p030050s002b.pdf 42.Morgan P, et al. Poster presented at IMCAS World Congress, 26–28 January 2023, Paris, France.43. Waibel J, et al. Poster presented at IMCAS World Congress. 01-03 February 2024. Paris, France. 44. Zubair R, et al. Dermatol Surg. 2024;50(12):1155-1162. 45.Oh S, et al. Antioxidants (Basel). 2023;12(6):1204. 46. Pfisterer K, et al. Front Cell Dev Biol. 2021;9:682414. 47.Kim HW, et al. Ann Dermatol. 2023;35(6):424–31. 48. Trevor LV, et al. J Clin Med. 2020;9(7):2161. 49.Aziz J et al. Skin Pharmacol Physiol. 2016;29(4):190–203. 50. Swift A et al. Aesthet Surg J. 2021;41(10):1107–19. 51.Vierkötter A, Krutmann J. Dermatoendocrinol. 2012;4(3):227–31.52. Zhang S, Duan E. Cell Transplant. 2018;27(5):729–38.53. Filho C DSM et al. Surg Cosmet Dermatol. 2013;5(4):345–50.54.Data on file (MA-48331). 55. Data on file (MA-54104) 56. Joseph J, et al. Poster presented at AMWC. 27-29 March 2024. Monte Carlo, Monaco. 57. Galderma. Data on file (MA-57540). 58.Vanaman M, Fabi S. Plast Reconstr Surg. 2015;136(5 Suppl):276S-281S. 59. Wilkerson E, Goldberg D. J Cosmet Dermatol. 2017;17(4):606-610.60. Coimbra D, et al. Surg Cosmet Dermatol 2012;4(2):182-5. 61. Mazzuco R, et al. J Cosmet Dermatol. 2022;21(12):6727-6733. 62. Lin M, et al. Dermatol Surg. 2020;46(3):386-394. Document ID GL-SCU-2400130
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